Single-Synapse Analysis of a Diverse Synapse Population: Proteomic Imaging Methods and Markers
نویسندگان
چکیده
منابع مشابه
Single-Synapse Analysis of a Diverse Synapse Population: Proteomic Imaging Methods and Markers
A lack of methods for measuring the protein compositions of individual synapses in situ has so far hindered the exploration and exploitation of synapse molecular diversity. Here, we describe the use of array tomography, a new high-resolution proteomic imaging method, to determine the composition of glutamate and GABA synapses in somatosensory cortex of Line-H-YFP Thy-1 transgenic mice. We find ...
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ژورنال
عنوان ژورنال: Neuron
سال: 2010
ISSN: 0896-6273
DOI: 10.1016/j.neuron.2010.09.024